The two AFC West squads will face off in the desert on Sunday afternoon. After six weeks of dealing with turf toe, San Francisco 49ers quarterback Brock Purdy will be back in action on Sunday, Nov. 16 as his team travels to take on the Arizona Cardinals.

The Niners are coming off a win over the Arizona Cardinals in which the offense looked full-strength with Brock Purdy and Ricky Pearsall back as Christian McCaffrey shone as a receiver.

Arizona had the passing game working, but it didn't matter in a 41-22 loss to San Francisco at State Farm Stadium in Glendale.

Catch Bryce Young and the Panthers (6-5) against Brock Purdy and the 49ers (7-4) at 8:15 p.m. ET on ESPN with streaming options available.