An analysis of an unusual enzyme could result in a new generation of antimicrobial medicines to counter antibiotic resistance ...
Researchers present novel therapeutics that rejuvenate a previously undruggable mitochondrial regulator of aging through a new mode of enzyme activation. Disclaimer: AAAS and EurekAlert! are not ...
BioRxiv (2023) PubMed PMID: 37546940; PubMed Central PMCID: PMC10402079. The mammalian innate immune system uses cyclic GMP–AMP synthase (cGAS) to synthesize the cyclic dinucleotide 2′,3′-cGAMP during ...
This method allows specific delivery of anti-cancer prodrugs to tumor cells using affibody conjugation, to avoid unwanted off-target effects and increase the time between drug doses. Antibody-directed ...
Traditionally developed antibiotics generally act inhibiting essential bacterial enzymes. However, new strategies are urgently needed to discover novel antibiotics against bacterial infections, such ...
Show More UCLA Geffen School of Medicine, Los Angeles, CA; UCLA Oncology Research Network, Los Angeles, CA; NewBiotics, San Diego, CA; USC Keck School of Medicine, Los Angeles, CA ...
A multicolored 3D model of an enzyme binding double-stranded DNA against a light purple background Computational enzyme design could allow for reactions not seen in nature. Credit: Ian Haydon ...
Life has evolved over billions of years, adapting to the changing environment. Similarly, enzymes—proteins that speed up biochemical reactions (catalysis) in cells—have adapted to the habitats of ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results