BIOENGINEER

New Algorithm Simulates Gene Frequency Histories Exactly, Even as Populations Change Size

Researchers have unveiled EWF 2.0, an exact simulation algorithm that generates statistically perfect allele frequency ...
BIOENGINEER

How Big Must a DNA Database Be? Massive Argentine Study Redefines Forensic Sampling Rules

A study of 8,237 Argentines genotyped at 22 autosomal STR loci shows that forensic parameters remain stable at modest sample ...
Nanowerk

Allele frequency

Allele frequency, or gene frequency, is the relative frequency of an allele (variant of a gene) at a particular locus in a population, expressed as a fraction or percentage. Specifically, it is the ...
ascopubs.org

Variant allele frequency of circulating tumor DNA mutations detected in preoperative blood is indicator for lymph node metastasis in early stage lung cancer.

The genomic landscape of immune-related genes and its correlations with TMB and PD-L1 expression in Chinese NSCLC. This is an ASCO Meeting Abstract from the 2020 ASCO Annual Meeting I. This abstract ...
Nature

Variation across the allele frequency spectrum

A new study finds that individuals with high plasma triglyceride levels carry approximately twice as many rare, coding genetic variants within four candidate genes identified through genome-wide ...
ascopubs.org

Relative Mutant Allele Frequency Role in ctDNA-Guided Anti–Epidermal Growth Factor Receptor Rechallenge in Metastatic Colorectal Cancer

Small Cell Lung Cancer Transformation in Actionable Genomic Alteration–Negative Non–Small Cell Lung Cancer With Response to Tarlatamab: A Case Report In this report, we present two real-world cases ...