New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Ethosuximide, a T-type calcium channel blocker, demonstrated no significant benefit as a treatment for patients with ...

Myotonic dystrophy is one of the most common forms of muscular dystrophy. It is a genetic condition that causes progressive muscle weakness and wasting. No treatments currently exist that slow the ...

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these ...

Lario Therapeutics has secured $2.4 million in new grant funding from The Michael J Fox Foundation for Parkinson’s Research ...

New prestigious grants support Lario's unique portfolio of calcium channel programmes -- Indication expansion into Parkinson's disease, and PTSD (post-traumatic stress disorders) -- Builds on prior ...

New York University (NYU) researchers suggest that ORAI1 calcium channel activity in oral cancer cells could be targeted to reduce the growth of oral tumors and reduce pain, according to a study that ...

A team of researchers has found that mutations in the calcium channel protein RyR1 that confer susceptibility to malignant hyperthermia make the protein hypersensitive to heat, which triggers ...

In a recent study posted to the bioRxiv* preprint server, researchers investigated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) envelope (E) protein activity in terms of calcium ...

Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by modulating the calcium ...