Reactive oxygen species (ROS) produced naturally during cellular metabolism often cause oxidative damage to cells. However, ...

Researchers at Texas A&M Health and collaborators have developed engineered CRAC channel inhibitory binders that can ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

Phosphoinositides are a family of membrane lipids distinguished by phosphate groups at specific positions on the inositol ring, acting as spatial and temporal organisers of cell activity. Through ...

Calcineurin is a ubiquitous serine/threonine phosphatase that decodes calcium signals to regulate an array of cellular functions. Its activation requires calcium binding to calmodulin and the ...

BPC-157 and TB-500, originating from gastric and thymic sources respectively, both influence angiogenesis, cytoskeletal ...

Omaveloxolone (approved for Friedreich's ataxia) may help protect cells from stress and correct underlying dysfunction in SMA ...

One of the most important mechanisms is receptor-mediated signaling. A peptide attaches to a specific receptor on the cell surface, which then activates intracellular proteins such as kinases or ...

Researchers from the Keck School of Medicine of USC have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response to cancer in mice—effectively ...

Heart cells constantly adapt to physical stress, and understanding this process may help improve future approaches to heart ...

Researchers at the Keck School of Medicine of University of Southern California (USC) have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response ...