Comparative genomic hybridization (CGH) was developed to identify pathogenic DNA copy-number changes (e.g., duplications, deletions) on a genome-wide scale, and to map these changes to genomic ...

The use of cell-free DNA (cfDNA) obtained from maternal plasma to perform noninvasive prenatal screening has been rapidly integrated into the care of pregnant women who are at high risk for fetal ...

When cancer spreads from a primary tumor to new sites throughout the body, it undergoes changes that increase its genetic complexity. A new study from researchers at Memorial Sloan Kettering Cancer ...

CN signatures were prevalent across cancer types and associated with diverse processes including focal tandem duplications, seismic amplifications, genome-wide loss of heterozygosity (gLOH), and HRD.

Young, Empowered and Strong: A Web-Based Education and Supportive Care Intervention for Young Women With Breast Cancer Across the Care Continuum To overcome these challenges, we have developed a ...

Determining the number of copies of a double stranded DNA template (be it genomic DNA, plasmid or an amplified fragment) is essential for many genetic quantification applications in research and ...