First came AlphaFold. Now comes AlphaGenome for DNA. When scientists first sequenced the human genome in 2003, they revealed the full set of DNA instructions that make a person. But we still didn’t ...
The much-heralded Human Genome Project was a huge milestone for science, but most of that genetic blueprint came from one man from Buffalo, N.Y. On Wednesday, May 10, 2023, scientists announced they ...
R-loops are structures that form when a strand of RNA (red) forms a stable structure with double-stranded DNA, causing one strand of the DNA to form a loop. R-loops are associated with gene ...
Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...
By setting up both reactions side by side in a test tube, the team revealed a literal tug-of-war between two DNA-repair pathways acting on the same HTT repeat. Which side wins likely determines ...
Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...
A tiny percentage of our DNA—around 2%—contains 20,000-odd genes. The remaining 98%—long known as the non-coding genome, or ...
Researchers at Kyushu University have revealed how spatial distance between specific regions of DNA is linked to bursts of gene activity. Using advanced cell imaging techniques and computer modeling, ...
To our immune system, a potentially lifesaving gene therapy can look a lot like a dangerous infection. That's because most ...
A new gene-editing technique enables the correction of multiple genetic mutations simultaneously, transforming the prospects for millions living with complex inherited diseases, such as cystic ...
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