To determine whether the interaction between sclerostin loop3 and LRP4 was required by sclerostin to antagonize Wnt/β-catenin signaling and inhibit bone formation We identified the interaction ...
The alternative text for this image may have been generated using AI. In this work, we investigated the roles of sclerostin loops using both genetic and pharmacologic approaches in vitro. For ...
A research team led by Hong Kong Baptist University (HKBU) has identified a molecular target for bone anabolic therapies using a selected aptamer that serves as an inhibitor of sclerostin, a protein ...
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