Researchers from Karolinska Institutet have discovered how mammalian cells prevent the gradual buildup of harmful mutations in mitochondrial DNA, the small but vital genome that powers every cell. The ...

Mitochondrial damage-associated molecular patterns (mtDAMPs) comprise a suite of endogenous molecules—including mitochondrial DNA (mtDNA), N-formyl peptides and cardiolipin—that are released when ...

Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...

For more than a century, heredity has been framed through the tidy logic of Mendel's pea plants: traits pass from parent to offspring by fixed genetic rules. But a new mouse study suggests that ...

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune defenses primed. Now researchers have identified a previously unknown form of ...