Optogenetic activation of silent VIP inhibitory neurons restores learning and motor function in Huntington's disease models.
Researchers identified VIP inhibitory neurons in Huntington’s disease and used optogenetics to restore motor neuron activity in mice.
Their proposed mapping strategies, outlined in two Nature Neuroscience papers, combine holographic optogenetics, a method to selectively and precisely stimulate or silence specific neuron populations, ...
Two different research groups, one based at Columbia University and UC Berkeley, and the other at the Vision Institute of Sorbonne University in Paris, introduced a promising approach to study ...
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