Nature

Astrocytic pleiotrophin deficiency in the prefrontal cortex contributes to stress-induced depressive-like responses in male mice

Astrocytes are closely linked to depression, and the prefrontal cortex (PFC) is an important brain region involved in major depressive disorder (MDD). However, the underlying mechanism by which ...
Nature

Elevated dorsal medial prefrontal cortex to lateral habenula pathway activity mediates chronic stress-induced depressive and anxiety-like behaviors

The medial prefrontal cortex (mPFC) sends projections to numerous brain regions and is believed to play a significant role in depression and anxiety. One of the key downstream targets of the mPFC, the ...
PsyPost on MSN

Study finds altered glutamate concentrations in specific brain areas of adolescents with ADHD

A neuroimaging study of adolescents with ADHD found age-related increases in glutamate levels in the medial prefrontal cortex ...
Medical Xpress

Neuron populations in the medial prefrontal cortex shown to code the learning of avoidant behaviors

Over the course of their lives, animals form associations between sensory stimuli and predicted threats or rewards. These associations can, in turn, shape the behaviors of animals, prompting them to ...
Psychology Today

Prefrontal Cortex in Horses and Humans

Many horse owners think the existence of the prefrontal cortex is a major controversy in equine science. It’s not. It’s just an area that’s riddled with misinformation. Curiously, most people—horsey ...
PsyPost on MSN

Researchers discover that brain wave patterns at age nine can predict mood disorders years later

Brain wave patterns measured during childhood can accurately predict whether a child is likely to experience anxiety or ...