Tau proteins play an important role in our normal brain function, mainly by helping to stabilize neurons in the brain. But in Alzheimer’s disease, tau proteins can misfold and tangle inside neurons.

Tau proteins act like the brain's maintenance crew, helping maintain the structure and proper function of brain cells. In ...

This discovery is important because it suggests a safer way to treat Alzheimer’s disease. Instead of trying to reduce essential brain chemicals, future treatments could focus on enhancing the brain’s ...

In Alzheimer's Disease and other neurodegenerative dementias, proteins that normally play a role in healthy brain tissue turn bad, clumping together to form insoluble plaques and tangles as neurons ...

The traditional view of tau is that of a rather dull microtubule-binding protein that occasionally goes rogue, wandering off into other cellular compartments where it stokes neurodegeneration. At ...

In Alzheimer's Disease and other neurodegenerative dementias, proteins that normally play a role in healthy brain tissue turn bad, clumping together to form insoluble plaques and tangles as neurons ...

The research group led by Prof. Wang Chu from the College of Chemistry and Molecular Engineering at Peking University published a research article entitled "Quantitative Chemoproteomics Reveals ...

Utilizing cutting-edge proteomics, researchers at the Buck Institute and elsewhere have mapped the “tau interactome” uncovering new findings about the role of tau in neurodegenerative disease.

Tau proteins play an important role in Alzheimer's disease. Tau helps to stabilize neurons in the brain, but in Alzheimer's disease, tau proteins can misfold and tangle inside neurons. These tangles ...