Eledon Pharmaceuticals’ lead asset, tegoprubart, is going to late-stage trials in kidney transplant rejection prevention, despite missing its primary efficacy endpoint. In the Phase II BESTOW trial ...

Rutgers Health researchers and other medical scientists involved in a large international study have identified new signs of kidney transplant rejection that could lead to more precise diagnosis and ...

Researchers identified a natural 'brake' within the innate immune system: the inhibitory receptor Siglec-E (SigE) and its human counterparts, Siglec-7 and Siglec-9. This receptor helps prevent ...

If an organ in your body (such as the heart, kidneys, or liver) is not working well enough because of an illness or injury, you may need an organ transplant. An organ transplant involves surgically ...

More than 50% of lung-transplant recipients experience a rejection of their new lung within five years of receiving it, yet the reason why this is such a prevalent complication has remained a medical ...

Johns Hopkins scientists and partners across the country are conducting research that could dramatically improve transplants, ...

In August, we reported on the decision by the Centers for Medicare & Medicaid Services (CMS) to not pursue a proposed Medicare policy that would have restricted coverage of a blood test used to ...

More than 50% of lung-transplant recipients experience a rejection of their new lung within five years of receiving it, yet the reason why this is such a prevalent complication has remained a medical ...

Researchers showed promising results using unique acute cellular rejection (ACR) and antibody-mediated rejection (AMR) microRNA panels to identify rejection after heart transplantation. There was an ...

Current treatments to prevent organ transplant rejection focus mainly on suppressing T cells, part of the adaptive immune system. However, the innate immune system—the body's first line of defense ...