Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...

Imagine owning a camera so powerful it can take freeze-frame photographs of a moving electron—an object traveling so fast it could circle the Earth many times in a matter of a second. Researchers at ...

The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...

Imaging large cleared tissues requires scaling the throughput of imaging techniques. Light sheet microscopy is a promising technique for high-throughput imaging; however, its reliance on conventional ...

Using a "spooky" phenomenon of quantum physics, researchers have discovered a way to double the resolution of light microscopes. Using a "spooky" phenomenon of quantum physics, Caltech researchers ...

The alternative text for this image may have been generated using AI. In this review, we will look ahead and discuss potential future avenues of fluorescence imaging with light-sheets. We will ...

QIScope: When imaging low protein levels in live cells on the high-sensitivity QIScope, bioluminescence (blue) significantly outperforms fluorescence (green). (Courtesy: Ruyu Ma - Helmholtz Munich) A ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

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Using a “spooky” phenomenon of quantum physics, Caltech researchers have discovered a way to double the resolution of light microscopes. In a paper appearing in the journal Nature Communications, a ...