CRISPR–Cas13—a class 2 type VI RNA endonuclease with two higher eukaryotes and prokaryotes nucleotide-binding (HEPN) domains for RNA cleavage—targets and degrades RNA. The RNA targeting has been used ...

Researchers at ETH Zurich in Basel report they have used CRISPR-Cas technology to decipher how mutations in a cell’s genome affect its function. With their new approach, the researchers can generate ...