The San Francisco 49ers got a game-winning TD from Christian McCaffrey that showed how deep Kyle Shanahan was in his bag.

San Francisco 49ers running back Christian McCaffrey reacted to the devastating injury suffered by George Kittle on Sunday.

Up next for the 49ers are the No. 1-seeded Seattle Seahawks, who defeated San Francisco in Week 18, 13-3, to earn the ...

Brock Purdy threw a 4-yard touchdown pass to Christian McCaffrey, leading San Francisco to a 23-19 victory over defending ...

PHILADELPHIA — Brock Purdy threw a go-ahead 4-yard touchdown pass to Christian McCaffrey late in the fourth quarter, San ...

The 49ers head to top-seeded Seattle next weekend for an NFC divisional playoff game. The NFC West rivals split the season ...

George Kittle's Achilles injury heaped adversity onto decimated Niners, but San Francisco outlasted the Eagles to set up ...

No problem for the San Francisco 49ers. Behind a valiant effort from Brock Purdy, Christian McCaffrey and an undermanned ...

The San Francisco 49ers went into Philadelphia and upset the Eagles, 23-19, behind Christian McCaffrey's two touchdowns and ...

QB-turned-WR Jauan Jennings shocked the Eagles with a version of their own trick play for another playoff touchdown pass to ...

The 49ers lost George Kittle but upset the defending Super Bowl champions with two fourth-quarter touchdowns in an NFC ...

Which team faces the most pressure? Who wins the NFC? Who takes the AFC? The Athletic's NFL writers break down this year's ...