Patrick Mahomes and Andy Reid lost 3 in a row to Lou Anarumo's Cincinnati defense. Can Anarumo bring that same unpredictability Sunday with Colts?

In Anarumo's first season as the Colts ' defensive play caller, this unit ranks ninth in points per game allowed. Indianapolis is also seventh in yards per rush and 15th in yards per pass surrendered. The Colts are also near the top of the NFL in interceptions.

Anarumo has seemingly had Mahomes and Reid’s collective number over the years, especially after climbing out to a 3-0 record against the two, but the Chiefs have rebounded in recent memory to tie up the series and force a Game 7.

Don't be surprised if Lou Anarumo's name returns to the surface during the hiring cycle. The Colts defensive coordinator just might land the job he missed out on a few years ago.

Sauce Gardner, the newest Colt, spent his bye week reflecting on the opportunity ahead but also found himself beginning to pile on pressure of rising to the moment. What defensive coordinator Lou Anarumo told him unprompted made Gardner feel like Anarumo was reading his mind.

Though he's yet to land head coaching experience, long-time NFL assistant and Colts defensive coordinator Lou Anarumo seen as possible candidate for newly-opened Giants head coach position.

The Colts hired Anarumo, who has been dubbed "The Mad Scientist", as a change of pace from former defensive coordinator Gus Bradley. Anarumo's scheme emphasizes simulated pressures and man coverage, making it an aggressive but successful scheme when used correctly.

The Indianapolis Colts debuted a cornerback group featuring Sauce Gardner, Charvarius Ward Sr., and Kenny Moore II last Sunday, which eased defensive coordinator Lou Anarumo's nerves throughout the game.