A phase 3 study is ongoing to confirm the survival benefit of venetoclax plus azacitidine in patients with treatment-naive high-risk MDS. The combination of venetoclax plus azacitidine was well ...

IgG4-RD in the urinary tract can often mimic symptoms of malignancy. A middle-aged male patient with an initial presentation of left flank pain underwent investigations that confirmed a diagnosis of ...

This is the first reported case of a child with PWS who was further diagnosed with LGS. “To our knowledge, this is the first reported case of LGS in a pediatric patient with Prader-Willi syndrome in ...

Having RA and type 1 diabetes increased the risk of developing PAH, and a link was found between a genetic risk of PAH and an increased risk of PAH. Bidirectional Mendelian randomization (MR) analysis ...

Patients with splenomegaly had significantly poorer overall survival compared to patients without splenomegaly. Cytopenia and splenomegaly are key prognostic determinants following the discontinuation ...

Women with Glanzmann thrombasthenia and twin pregnancies have an elevated risk of significant hemorrhage, requiring specialized management. Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a ...

Statistical analysis revealed that severe cytopenia and splenomegaly were significant prognostic factors for survival. Cytopenia and splenomegaly appear to be the main drivers for poor prognosis in ...

Patients with prior metformin use had a 60% higher likelihood of developing MDS after adjusting for confounders. Prior exposure to metformin in patients with diabetes mellitus (DM) was associated with ...

There is an ongoing need for standardized guidelines and global screening initiatives to facilitate early diagnoses of hematologic disorders such as fetal and neonatal alloimmune thrombocytopenia ...

(L-R) David Allison, CEO of TREAT-NMD Services; Tim Miller, MD, vice president, enterprise science and innovation at Thermo Fisher Scientific; and Barry Byrne MD, PhD, associate chair of pediatrics ...

Smaller volumes of the claustrum were associated with poorer clinical performance scores and predicted poorer neurological performance out to 5 years. Loss of claustrum volume may have a significant ...

The findings of this study are in accordance with existing literature in confirming the effectiveness and safety of emicizumab in hemophilia A. Emicizumab is an effective prophylaxis in terms of the ...