Researchers say discovery could establish the basis for a novel, tandem biomarker-peptide therapeutic approach to schizophrenia.

Discover how CRISPR genome editing is revolutionizing medicine. Learn the science of Cas9, current clinical trials, and the future of gene editing.

Background High serum levels of interleukin 6 (IL-6) predict poor prognosis in intrahepatic cholangiocarcinoma (iCCA), a malignancy that often develops in a chronically inflamed milieu . Here, tumour ...

Human genes are written in long strings of three-letter units composed of four different nucleotides. These units—or ...

Dosed multiple Rett syndrome patients in REVEAL pivotal trial of TSHA-102, with enrollment advancing across multiple sites; on track to complete ...

Researchers discover that a mutation in the grin2a gene impairs a thalamocortical brain circuit, preventing the brain from ...

One of the symptoms of schizophrenia is difficulty incorporating new information about the world. This can lead patients to struggle with making decisions and, eventually, to lose touch with reality.

To understand the human genome, scientists focused on protein-coding genes and their functions for decades. This has given us ...

The genomes of phages—viruses that infect bacteria—are largely composed of "dark matter": genes that encode proteins whose functions remain unknown. Less than four years ago, a team led by Prof. Rotem ...

Haunted by the cystic fibrosis patients he could not help, one Iowa doctor commits his life to understanding what is broken deep inside their cells.