Alfred Collins isn't your typical 49ers defensive tackle. Collins is built to defend the run. He's big and extremely difficult to move.

After drafting Georgia edge rusher Mykel Williams in the first round, the San Francisco 49ers doubled down on rebuilding their defensive front by selecting Texas Longhorns defensive tackle Alfred Collins with the 43rd overall pick in the second round of the 2025 NFL Draft.

The San Francisco 49ers selected Texas DL Alfred Collins with the No. 43 overall pick in the 2025 NFL draft. 'Strong as an ox' is a phrase that comes to mind when describing Alfred Collins' game. He has good size, length and strength to be an effective run defender at the next level.