Louisville Metro Police is asking citizens to avoid walking on local interstates after a pedestrian was hit and killed on ...

A wreck is causing major delays on Interstate 65 Thursday morning.The crash is on the northbound side of the interstate, ...

An explosion and semi-truck fire in northwest Indiana has closed a section of Interstate 65 in both directions, police said.

Interstate 65 Southbound at Exit 230 near Demotte, Indiana is down to one lane after a semi-truck caught fire Monday ...

LOUISVILLE, Ky. (WDRB) -- A man was hit and killed on Interstate 65 near hospital curve early Friday morning after reportedly ...

Clean-up efforts are underway after a raging fire consumed a semi-truck on Interstate 65 in northwest Indiana.

A local construction company had to be called in late Monday to replace part of Interstate 65 that was damaged when a semi ...

LOUISVILLE, Ky. (WDRB) — Interstate 65 North at University Boulevard, near UofL, has reopened after a crash Friday evening.

Milestone Contractors will begin construction on I-65 Safety and Efficiency, a project to improve safety and traffic flow on ...

The extent of the injuries was unknown. Drivers can expect some delays on Highway 65 near Wheatland. See our live traffic map for updates. This story was curated by Hearst's KCRA Alert Desk.

A semi-truck reportedly hauling petroleum burst into flames and closed all lanes of traffic on Interstate 65 in Jasper County. The Indiana Department of Transportation said the ...