Police believe Daryus Chambers, 37, crashed into a tractor-trailer and then was run over by another motorcyclist.

An Antioch man died Friday night after a crash involving two motorcycles and a tractor-trailer on Interstate 65 in Nashville.

Lane closures will continue to affect drivers in downtown Louisville this weekend as road work on Interstate 65 continues.

A Gary man was killed on Interstate 65 late Saturday night when he was struck by another vehicle while trying to put fuel in ...

Construction work in the notorious “Hospital Curve” corridor of Interstate 65 South wrapped up early, but more lane closures and traffic headaches are on the way for Louisville drivers.

A pedestrian was hit and killed on Interstate 65 in northwest Indiana over the weekend, Indiana State Police said Monday.

Nearly a year after a member of a Tennessee Department of Transportation trash pickup crew was hit along Interstate 65, ...

A woman was found dead in a hit-and-run on Interstate 65 at Interstate 59/20. The Jefferson County Coroner’s Office on ...

A single-vehicle crash on Interstate 65 has led to a complete road closure near mile marker 306. The incident occurred at ...

I-65 South will reopen at 5 a.m. Monday, July 28. The Kentucky Transportation Cabinet said once the interstate reopens Monday, I-65 South will be reduced to one lane through the corridor until ...

The Greenwood Fire Department has confirmed that one person died in a plane crash a mile away from the Indy South Greenwood ...

The Alabama Department of Transportation will begin a pavement preservation project on Interstate 65 in Butler County on Thursday, July 31.