The 49ers were among the preseason favorites to win the Super Bowl, but now they look like long shots to make the playoffs.

San Francisco 49ers running back Christian McCaffrey could be done for the season after just four games. As head coach Kyle ...

The San Francisco 49ers received some brutal news on Sunday evening. According to head coach Kyle Shanahan, running back ...

The San Francisco 49ers' losses to the Green Bay Packers and Buffalo Bills mark the worst two-game stretch by a defending ...

The Buffalo Bills easily got past the San Francisco 49ers 35-10 on a snowy Sunday Night Football matchup. Here are winners ...

The 49ers were absolutely shellacked Sunday for a second straight week as the Buffalo Bills beat them 35-10 on national ...

San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

Coming into the 2024 NFL season, it wouldn't have been out of the ordinary to find a Super Bowl prediction featuring the ...

"49ers coach Kyle Shanahan tells reporters that RB Christian McCaffrey suffered a PCL injury that could end his season. Just ...

Christian McCaffrey's 2024/25 NFL season could be over in a devastating blow to the San Francisco 49ers after the 28-year-old ...

After Sunday night's humbling loss in snowy Buffalo, it's time for Kyle Shanahan and John Lynch to start shutting ...