San Francisco has been up and down all season, but the Super Bowl hangover appears to be happening after the 49ers got ...

San Francisco played without four key players - quarterback Brock Purdy, left tackle Trent Williams, defensive end Nick Bosa ...

Soon, quarterback Brock Purdy is likely to command a $50 million annual pay raise, and if the 49ers do extend him, they'll ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...

The banged-up 49ers suffered a blowout loss to the Packers on Sunday, and their playoff outlook is becoming more bleak.

Taking the field in Week 1 with sky-high expectations, what with eight-year head coach Kyle Shanahan having just taken his ...

John Lynch discussed San Francisco's lack of discipline with NBC Sports Bay Area's Matt Maiocco on "49ers Game Plan." ...

How have Super Bowl odds changed over the last week? Let's take a look at the most recent sports betting odds for Super Bowl ...

Under head coach Kyle Shanahan, the San Francisco 49ers have spent years falling just inches short of the franchise’s sixth ...

The San Francisco 49ers expect to get quarterback Brock Purdy back for their Week 13 matchup with the Buffalo Bills. That’s ...

The star-studded lineup of Jon Batiste, Trombone Shorty, Lauren Daigle and Ledisi honors the legendary music scene of New ...

Having a 5-6 record entering Week 13 isn't how the San Francisco 49ers drew it up. Injuries have played a part in their ...