The San Francisco 49ers are talented enough to win the Super Bowl, but the defending NFC champions have a lot of work to do. At 5-6, the 49ers face a must-win game against the Buffalo Bills on Sunday.
At +7500 as of Nov. 30, the SanFrancisco49ers aren't among the favorites to win the SuperBowl this season. The 49ers picked up a 38-10 loss to the Green Bay Packers in their last game.