About - eLife
eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science.
Latest research | eLife
Oct 29, 2024 · eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock corporation incorporated in the State of Delaware ...
How to measure and evaluate binding affinities | eLife
Aug 6, 2020 · Quantitative measurements of biomolecule associations are central to biological understanding and are needed to build and test predictive and mechanistic models. Given the advances in high-throughput technologies and the projected increase in the availability of binding data, we found it especially timely to evaluate the current standards for ...
Memory: How the brain constructs dreams - eLife
Jun 8, 2020 · Complexin determines magnitude and kinetics of synchronized secretion, but the underlying molecular mechanisms remained unclear. Here, we show that the hydrophobic face of the amphipathic helix at the C-terminus of Complexin II (CpxII, amino acids 115–134) binds to fusion-promoting SNARE proteins, prevents premature secretion, and allows vesicles to accumulate in a release-ready state in ...
Magazine - eLife
eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that encourages and recognises the most responsible behaviours in science. eLife Sciences Publications, Ltd is a limited liability non-profit non-stock …
Development: Investigating the origin of insect metamorphosis
Dec 21, 2023 · Given Darwin’s longstanding interest in entomology, it is possible he had insects and metamorphosis in mind when he wrote about “endless forms most beautiful” in the final sentence of On the Origin of Species.More than half of the 2.2 million animal species that have been described are insects, and 98% of these undergo some form of …
Publishing and peer review at eLife · eLife
2 Peer review. eLife editors - who are all active researchers - discuss new submissions and decide which will be peer reviewed. The criteria used by the editors are discussed in “How and why eLife selects papers for peer review”.. Each peer reviewer is asked to write a Public Review of the article, and to recommend ways in which the authors could improve it.
Lung evolution in vertebrates and the water-to-land transition
Jul 26, 2022 · All life on Earth started out under water. However, around 400 million years ago some vertebrates, such as fish, started developing limbs and other characteristics that allowed them to explore life on land. One of the most pivotal features to evolve was the lungs, which gave vertebrates the ability to breathe above water. Most land-living vertebrates, including humans, have two lungs which sit ...
Mutations: Stop that nonsense! - eLife
Sep 9, 2014 · eLife 3:e04300. Genetic mutation is a major risk for living cells. Direct damage to DNA or errors in the processes that generate messenger RNA (mRNA) from the DNA template can introduce mutations, with potentially harmful consequences. ‘Nonsense’ mutations are particularly problematic: they are associated with many genetically inherited ...
Open Knowledge Maps: A visual interface to the world’s ... - eLife
Feb 26, 2020 · Introduction. Open Knowledge Maps is a charitable, non-profit organization dedicated to dramatically increasing the visibility of scientific knowledge for science and society alike. Headquartered in Vienna, Austria, Open Knowledge Maps comprises an international community including team and supporting members, advisors and partner organizations.